Download Alzheimer’s and Parkinson’s Disease: Strategies for Research by I. Hertman (auth.), Abraham Fisher, Israel Hanin, Chaim PDF

By I. Hertman (auth.), Abraham Fisher, Israel Hanin, Chaim Lachman (eds.)

This publication is the result of a world convention, held on the Aviya Sonesta inn in Eilat, Israel, on March 24-27, 1985. This used to be the thirtieth in a sequence of the yearly OHOLO meetings, subsidized through the Israel Institute for organic examine. individuals during this convention consisted of scientists from 4­ teenager nations; represented a vast spectrum of analysis pursuits; and incorporated a well-balanced illustration from academia, scientific associations and pharmaceutical undefined. The booklet comprises talks, poster classes, and a complete common dialogue, all from the lawsuits of this convention. within the curiosity of assuring a quick ebook of the unconventional infor­ mation reviewed, this ebook has been ready in camera-ready structure. we're cognizant of the truth that a number of typographical mistakes may possibly exist within the textual content, and that there are diversifications fashionable and typeface of the var­ ious chapters. This, we felt, was once an affordable compromise for the sake of velocity and effective transmission of worthy clinical info. No­ physique is ideal . •••• The good fortune of the convention, and as a result the standard of this publication are caused by the large efforts of a big variety of tremendous able participants. those contain contributors of the clinical Organizing Committee, and the Technical employees of the OHOLO association. after all, the convention couldn't have succeeded with no the top of the range of the displays, and the enthusiastic participation of the contributing scientists.

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Extra resources for Alzheimer’s and Parkinson’s Disease: Strategies for Research and Development

Example text

For example. there are considerab ly more plaques in the inoculated hemisphere than in the contralateral hemisphere (Bruce and Fraser 1981). A relation betweem amyloid formation and infectivity is also implied by finding that large masses of amyloid are found in the needle track formed by the intracerebral inoculation of scrapie into mice (Wisniewski et a1. 1981c). These data have led us to propose the following sequence of events in the pathogenesis of neuritic and amyloid plaque formation. 1.

T •• and DeLong. R •• Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain. Science 215:1237-1239 (1982). Wisniewski. M •• Bruce. E •• and Fraser. -H .. Infectious etiology of neuritic (senile) plaques in mice. Science. 190:1108-1110 (1975). Wisniewski. M •• Iqbal. R •• Aluminum-induced neurofibrillary changes: Its relationship to senile dementia of the Alzheimer's type. Neurotoxicology 1:121-124 (1980). Wisniewski. B •• Evidence for blood-brain barrier changes in senile dementia of the Alzheimer type (SDAT).

L •• and DeLong. R •• Brain mechanisms in Alzheimer's disease. Hosp. Practice 17:55-63 (1982). Crapper. R •• Dalton. J •• Karlik. J •• DeBoni. U•• Role of aluminum in Alzheimer's disease. in. E. Alexander. P. Medical and Scientific Books. New York. pp. 89-111 (1981). Dahl. D•• Selkoe. T •• and Bignami. A•• Immunostaining of neurofibrillary tangles in Alzheimer's senile dementia with a neurofilament antiserum. J. Neurosci. 2:113-119 (1982). Davies. P •• Katzman. R•• and Terry. D •• Reduced somatostatin-like 33 immunoreactivity in cerebral cortex from cases of Alzheimer's disease and Alzheimer senile dementia.

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