Download Analysis of Microarray Data: A Network-Based Approach by Frank Emmert-Streib, Matthias Dehmer PDF

By Frank Emmert-Streib, Matthias Dehmer

This publication is the 1st to target the appliance of mathematical networks for reading microarray info. this technique is going way past the traditional clustering tools typically used.

From the contents:

  • Understanding and Preprocessing Microarray facts
  • Clustering of Microarray info
  • Reconstruction of the Yeast telephone Cycle by way of Partial Correlations of upper Order
  • Bilayer Verification set of rules
  • Probabilistic Boolean Networks as types for Gene law
  • Estimating Transcriptional Regulatory Networks by means of a Bayesian community
  • Analysis of healing Compound results
  • Statistical tools for Inference of Genetic Networks and Regulatory Modules
  • Identification of Genetic Networks through Structural Equations
  • Predicting useful Modules utilizing Microarray and Protein interplay info
  • Integrating effects from Literature Mining and Microarray Experiments to deduce Gene Networks

The ebook is for either, scientists utilizing the procedure in addition to these constructing new research options.

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Additional resources for Analysis of Microarray Data: A Network-Based Approach

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R. and Russell, S. (2006) Microarray oligonucleotide probes. Methods in Enzymology, 410, 73–98. , Tautz, D. A. (2007) Oligonucleotide microarrays: widely applied poorly understood. j23 24 j 1 Introduction to DNA Microarrays 66 67 68 69 70 71 72 73 Briefings in Functional Genomics and Proteomics, 6 (2), 141–148. , Stunnenberg, H. and Flicek, P. (2007) Optimized design and assessment of whole genome tiling arrays. Bioinformatics, 23 (13), i195–i204. Y. and Wang, Y. (2003) Effects of atmospheric ozone on microarray data quality.

R. (2004) Comprehensive comparison of six microarray technologies. Nucleic Acids Research, 32 (15), e124. C. and Szallasi, Z. (2005) Reliability and reproducibility issues in DNA microarray measurements. Trends in Genetics, 22 (2), 101–109. Review. , Mane, S. P. (2002) Microarray results: how accurate are they? BMC Bioinformatics, 233, 22. M. C. (2003) Evaluation of gene expression measurements from commercial microarray platforms. Nucleic Acids Research, 31 (19), 5676–5684. , Shi, L. D. (2006) Performance comparison of onecolor and two-color platforms within the MicroArray Quality Control (MAQC) project.

In addition, many protocols for array hybridization are suboptimal. Historically, quantitative PCR and Northern blots represent a standard method for measuring gene expression, and are used as a way to verify microarray results. It is common when performing Northern blot analysis, or qPCR, to optimize the probe j17 18 j 1 Introduction to DNA Microarrays and hybridization conditions. In a microarray experiment, all the probes are different, yet they all experience identical hybridization conditions.

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